netbackup appliance 5200

On the netbackup 5200 appliance, it states that it has the duplication procedures and replication, but when backing up the system to the 5200 , once the backup data its stored on the appliance does it replicates its self from the appliance to the dedicated data centers or is that from the software on the os the replicates to the data centers, for example= client os-->netbackup 5200-->data centers  or client--->datacenters, client --->netbackup 5200

thanks